Atorvastatin
Atorvastatin is an agent that inhibits the formation of cholesterol in the body and reduces the LDL cholesterol. In people with high cholesterol it can help to prevent heart and circulation problems such as strokes and heart attacks. It can also help reducing the chances of having certain heart and circulation problems in people who have already had them.
- Used for treating: high cholesterol.
- Medicine group: statins.
- Effect: lowers lipids and triglycerides in the blood.
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Using atorvastatin to lower cholesterol
Atorvastatin works by lowering the lipid levels in the blood. This occurs because it inhibits certain enzymes. When the enzymes can not be used, cholesterol is no longer produced. The effect of atorvastatin was confirmed in several large clinical trials.
The administration of Atorvastatin
You take atorvastatin just once a day at a moment of your convienience.
Normally you start with a dose of 10 mg of atorvastatin per day with a maximum of 80 mg per day.
Contraindications for using atorvastatin to lower blood pressure
You may not use Atorvastatin when:
- are a woman who is or could become pregnant; this medicine is not safe for the unborn child
- are over 70 years old
- are allergic or sensitive to or have had a bad reaction to statin or a fibrate or any of the other ingredients in the past
- are breast-feeding
- drink alcohol heavily
- have had a stroke
- have had transient ischaemic attacks
- have hypothyroidism
- have or have had lung, liver, or kidney problems
- have or have had a family history of muscle problems
- have or have had high blood pressure
- have or have had risk factors for developing diabetes or rhabdomyolysis
One should always ask a doctor or pharmacist for advice if you have doubts whether you can take atorvastatin.
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Atorvastatin side effects
Atorvastatin also has side effects which can occur frequently. Most side effects are mild, serious side effects are very rare.
Side effects can include:
- digestive problems such as bloating, nausea and constipation
- headaches and dizziness
- muscle cramps, muscle aches and joint pain
- insomnia
- rash
- inflammation of the liver
- allergic reactions to the drug
Interactions with atorvastatin
Examples of medicines that you should not take with atorvastatin at the same time, are:
itraconazole, clarithromycin, ritonavir and other CYP3A4 inhibitors
niacin
ciclosporin
fibrates
Make sure you always thoroughly fill out the medical questionnaire when ording Atorvastatin!
Warning: This medicine interacts with grapefruit juice. Grapefruit juice will increase the level of Atorvastatin calcium trihydrate in the blood and should therefore not be consumed while you are using Atorvastin.
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