Amlodipine
Amlodipine is a medication that can lower blood pressure. It is a calcium channel blocker with a long half-life, and therefore with a long-lasting effect. Amlodipine is prescribed to treat hypertension, but it is also used for treating and preventing attacks of angina pectoris and Prinzmetal’s angina.
- Used for treating: high blood pressure and angina pectoris.
- Effect: relaxes blood vessels, so that blood passes through the vessels more easily.
- Active ingredient: amlodipine besilate.
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How does Amlodipine work?
Amlodipine relaxes your blood vessels, therefore allowing bloodflow to the heart and other vital organs to occur more fluently. The blood vessels relax because the Amlodipine blocks certain calcium channels by binding to a subunit. Therefore less calcium flows into the smooth muscle cells, thus the tone of the muscle is reduced. As a result, the heart muscle cells contract less powerful and consume less oxygen. The muscles relax more, which dilates the blood vessels and blood flow gets easier.
In a normal dosage amlodipine affects most of the coronary arteries.
How often should I take Amlodipine 5mg?
You need to take Amlodipine only once a day, because of its long half-time.
Contraindications for using amlodipine tablets
You should not use amlodipine if you:
- are allergic or sensitive to or have had a bad reaction to dihydropyridines or any other ingredients in the past
- are in shock including cardiogenic shock
- are on dialysis
- are breastfeeding
- have certain types of heart problems or have recently had a heart attack
Warning: this medicine could affect your ability to drive or operate machinery.
Amlodipine tablets side effects
You might experience side effects of amlodipine. Examples include:
• edema of the legs
• headache, fatigue and dizziness
• facial flushing and heat waves
• palpitations of the heart
Interactions of Amlodipine 5 mg with other drugs:
You should not use Amlodipine when you also use:
• certain antidepressants such as nefazodone
• nitrates
• beta-blockers
• Sildenafil
• ketoconazole or itraconazole
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